Choosing the right hrt
Sajeel Abrar GPHC-2066354 Independent Prescribing Pharmacist · 12/09/2025 · 1 min read
Patches, gels, tablets or rings what suits your symptoms, lifestyle and health history?
Is all HRT the same?
Not at all. While all HRT works to replace hormones your body is no longer making, the type, route, and dose can make a big difference in how you feel. Your choice of HRT depends on your symptoms, medical history, preferences, and whether you still have a womb.
HRT delivery methods
HRT can be taken through the skin (transdermal) or by mouth (oral). Transdermal options like patches, gels, and sprays are often preferred because they carry a lower risk of blood clots. Oral HRT is still effective but may carry more risk for some women.
Combined or estrogen-only?
If you have a womb, you'll need combined HRT estrogen and progesterone to protect your uterus. If you've had a hysterectomy, estrogen-only HRT may be suitable. Some women use a Mirena coil for progesterone, alongside estrogen gel or patch.
Topical or local options
For vaginal dryness, discomfort or urinary symptoms, local estrogen (e.g. Vagifem, Ovestin, Imvaggis) can be used directly without affecting the rest of the body. These are very low dose and safe for most women, even if systemic HRT isn't suitable.
Still unsure?
That's okay. We'll guide you based on your symptom profile, blood pressure, family history and preferences. Most women feel better with the right plan and we review it regularly.
The takeaway
There's no one-size-fits-all. Choosing HRT is about finding a plan that meets your goals, fits your lifestyle, and supports your wellbeing now and long term.
"The best HRT is the one that works for you safely, effectively, and on your terms."
Written by Sajeel Abrar, Independent Prescribing Pharmacist • GPhC: 2066354
Last updated: 18 April 2026